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DISEASES IN NEWS: CHAGAS, KFD

Last Updated on 26th November, 2024
5 minutes, 47 seconds

Description

Source: ENTOMOLOGY

Disclaimer: Copyright infringement not intended.

Context

A study published in the Journal of Medical Entomology shows that Trypanosoma cruzi—the parasite that causes Chagas disease—can survive in dead kissing bugs (Triatominae) even within insecticide-treated dog kennels.

Karnataka is grappling with the outbreak of Kyasanur Forest Disease (KFD) commonly known as monkey fever. 

About Chagas Disease

Feature

Details

Causative Agent

Trypanosoma cruzi (a protozoan parasite).

Vector

Triatomine bugs (commonly known as kissing bugs).

Geographic Distribution

Endemic to Latin America increasingly reported globally due to migration.

Transmission

Vector bites, congenital (mother-to-child), contaminated food, organ transplants or blood transfusion.

Clinical Manifestations

Stage

Symptoms

Acute Stage

Fever, swelling at the bite site (Romaña sign), malaise, hepatosplenomegaly.

Chronic Stage

Asymptomatic for years; severe cases include cardiomyopathy, arrhythmias and gastrointestinal complications (megacolon, megaesophagus).

Treatment

Drugs

Details

Nifurtimox

Effective in the acute stage.

Benznidazole

Commonly used.

Global Impact

Affects 6–7 million people worldwide with significant morbidity in Latin America.

Migration and urbanization have spread cases to non-endemic regions including the U.S. and Europe.

About Kyasanur Forest Disease (KFD)

Feature

Details

Causative Agent

Kyasanur Forest Disease Virus (KFDV), a flavivirus.

Vector

Ticks (Haemaphysalis spinigera).

Reservoir Hosts

Small mammals, monkeys (Macaca radiata and Semnopithecus entellus).

Geographic Distribution

Endemic to Karnataka, Goa, Kerala, Tamil Nadu and Maharashtra in India.

Transmission

Tick bites; handling infected animal carcasses.

Clinical Manifestations

Stage

Symptoms

Febrile Phase (1st Week)

High fever, headache, chills, muscle pain, vomiting and diarrhea.

Post-febrile Phase

Hemorrhagic symptoms, neurological complications (meningitis, encephalitis).

Recovery Phase

Some patients experience prolonged weakness and fatigue.

Treatment

No specific antiviral treatment is available.

Symptomatic management includes hydration, pain relief and treatment of secondary infections.

KFD vaccine available for high-risk populations in endemic areas.

Global Impact

Reported 500–700 cases annually with fatality rates ranging from 3–10%.

Increasing human activities in forested areas have heightened the risk of transmission.

Chagas Disease vs. KFD

Aspect

Chagas Disease

Kyasanur Forest Disease (KFD)

Causative Agent

Trypanosoma cruzi (protozoan)

KFDV (flavivirus)

Vector

Triatomine bugs

Ticks (Haemaphysalis spinigera)

Primary Symptoms

Cardiac and gastrointestinal complications

Hemorrhagic fever, neurological symptoms

Geographic Scope

Endemic to Latin America, spreading globally

Restricted to forested areas in India

Treatment

Antiparasitics (nifurtimox, benznidazole)

Supportive care only

About Kissing Bugs

Kissing bugs, also known as Triatomine bugs, are blood-sucking insects responsible for transmitting Trypanosoma cruzi, the causative agent of Chagas disease. These insects are primarily found in the Americas and have a significant role in the epidemiology of the disease.

Biology

Feature

Details

Taxonomy

Family: Reduviidae; Subfamily: Triatominae.

Common Names

Kissing bugs, Assassin bugs, Cone-nose bugs.

Physical Characteristics

Oval-shaped body, 1–3 cm long, with a cone-shaped head and a long proboscis.

Habitat

Prefer cracks in walls, roofs, and spaces in thatched houses; can also be found in wild animal nests.

Feeding Habits

Nocturnal feeders; attracted to CO₂ and warmth from human and animal bodies.

Key Vector Species

Triatoma infestans: Common in South America.

Rhodnius prolixus: Found in Central America.

Triatoma dimidiata: Distributed widely in Central and South America.

Role in Chagas Disease Transmission

Kissing bugs feed on blood and defecate near the bite site.

The Trypanosoma cruzi parasites in their feces enter the human body through mucous membranes or scratches in the skin caused by itching.

Sources:

ENTOMOLOGY, TIMESOFINDIA

 

PRACTICE QUESTION 

Q:Which of the following statements about kissing bugs is/are correct?

  1. Kissing bugs are nocturnal insects that feed on blood.
  2. They primarily transmit malaria and dengue in tropical regions.
  3. These bugs can transmit Trypanosoma cruzi through their feces.

Select the correct answer using the codes given below:

(a) 1 and 2 only

(b) 1 and 3 only

(c) 2 and 3 only

(d) 1, 2, and 3

Answer: (b)

Explanation:

Statement 1 is correct. Kissing bugs are nocturnal insects that feed on the blood of humans and animals primarily at night.

Statement 2 is incorrect. Kissing bugs do not transmit malaria or dengue. These diseases are spread by mosquitoes like Anopheles and Aedes aegypti respectively.

Statement 3 is correct. Kissing bugs transmit Trypanosoma cruzi the causative agent of Chagas disease, through their feces which contaminates wounds or mucous membranes.

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